TRPV1相关论文
目的:探讨桂枝新加汤（GZXJD）治疗颈椎病,有效缓解疼痛的作用机制,为临床应用提供依据。方法:第一部分基于网络药理学与分子对接技术......
目的 观察祛风止咳方对咳嗽敏感性增高豚鼠模型TRPV1通路表达的影响,探讨其干预喉源性咳嗽的作用机制。方法 采用卵蛋白腹腔注射致......
《针灸和草药（英文）》编辑部联合天津中医药大学实验针灸学研究中心召开了2021年诺贝尔生理学或医学奖对针灸机理研究启示的学术研讨......
辣椒是日常生活中广泛食用的蔬菜和香料,辣椒素是辣椒中辣味的主要来源,具有抗肥胖、抗氧化、镇痛等作用。研究表明,辣椒素在低浓......
目的 探究瞬时电位香草醛受体1（transient potential vanillin receptor 1,TRPV1）在炎性疼痛发生发展中的作用。方法 采用Pubmed检索......
目的 研究三伏贴中有效成分芥子碱硫氰酸盐（Sinapine thiocyanate,SPT）和延胡索乙素（Tetrahydropalmatine,THP）对瞬时感受器电位离子通......
本文以2021年诺贝尔生理学或医学奖中温度感知机制的关键因子—TRPV1的作用机理及过程为情境命题素材，从试题的情境材料、命题立意......
疼痛和瘙痒是人体的重要感觉,是对外界有害刺激的一种保护机制。研究发现转录因子Runx1和Tlx3参与感觉神经元的发育调控:转录因子R......
目的 分析SFRP5、TRPV1、NT-pro-BNP在2型糖尿病周围神经病变中的表达及相关性.方法 将我院2018年1月至2019年12月间收治的99例单......
过敏性鼻炎（allergic rhinitis,AR）又叫做变应性鼻炎,是一种发生在鼻腔鼻粘膜由IgE介导的敏感性增高的慢性炎性疾病。过敏性鼻炎通常......
第一部分帕金森病小鼠模型制备及疼痛行为学评估目的:通过在小鼠左侧纹状体注射6-羟基多巴（6-OHDA）的方式构建单侧帕金森（parkinson’......
跨膜离子通道样蛋白家族（transmembrane channel-like protein,TMC）,包括8个成员TMC1-TMC8。根据基因同源性又可进一步分为3个亚家族......
TRPV1通道（Transient Receptor Potential cation channel subfamily V member 1,瞬时受体电位香草素受体亚型-1）是一个四聚体配体门......
背景:腰椎间盘突出症（Lumbar Disc Herniation,LDH）是临床骨科较常见疾病,以腰痛甚至腿痛为主要症状,其中腿部疼痛麻木为突出的椎间......
美国科学家David Julius和Ardem Patapoutian因辣椒素受体TRPV1和薄荷醇感受器TRPM8的突破性发现,揭示了温度感知的奥秘,由此获得......
目前还没有一种手段能够根治糖尿病,大多使用降糖药物控制血糖延缓病情进展,防治并发瘟从而改善患者生活质量.近年来,瞬态受体电位......
目的探讨吴茱萸次碱（rutaecarpine, Rut）对长寿蛋白SIRT1表达及AngⅡ诱导的血管平滑肌细胞（vascular smooth muscle cells, VSMCs）衰老......
目的:观察芎芷镇痛方对偏头痛大鼠三叉神经节瞬时感受器电位香草酸受体1（TRPV1）表达的影响,探讨芎芷镇痛方治疗偏头痛的作用机制。方......
目的:功能性消化不良（Functional Dyspepsia,FD）是消化科的常见病之一,其发病机制尚未完全明确,可能与内脏高敏感、消化道菌群的改变......
目的:瞬时受体电位香草素1（transient receptor potential vanilloid type-1,TRPV1）是细胞膜上非选择性阳离子通道,可被胞外质子、有......
目的:作为一种感受疼痛的离子通道,瞬时受体电位香草酸1（TRPV1）主要表达在哺乳动物的外周感觉神经元中。虽然TRPV1是一种典型的感受......
2021年诺贝尔生理学或医学奖授予戴维·朱利叶斯（David Jay Julius）和阿登·帕塔普蒂安（Ardem Patapoutian）,以表彰他们在发现温度与触......
2021年诺贝尔生理学或医学奖授予戴维·朱利叶斯(David Jay Julius)和阿登·帕塔普蒂安(Ardem Patapoutian),以表彰他们在发现温度......
Epilepsy is a brain condition characterized by the recurrence of unprovoked seizures.Recent studies have shown that comp......
Oxidative stress induces itch via activation of transient receptor potential subtype ankyrin 1 in mi
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Formaldehyde up-regulates TRPV1 through MAPK and PI3K signaling pathways in a rat model of bone canc
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TRPV1 induced apoptosis of colorectal cancer cells by activating calcineurin-NFAT2-p53 signaling pat
Objective Colorectal cancer(CRC)is one of the common malignant tumors of digestive system and its incidence is increasin......
目的 Long-term inhalation of cigarette smoke or air pollutants can both result in the cough hypersensitivity. Many resea......
IL-6-mediated functional up-regulation of TRPV1 receptors in DRG neurons via the activation of JAK/P
Objective Primary and metastatic cancers that affect bone are frequently associated with severe and intractable pain....
目的：观察隔药灸天枢穴(双)、气海穴对慢性炎性内脏痛大鼠脊髓背角SP、c-fos、TRPV1表达的影响,探讨隔药灸对慢性炎性内脏痛镇痛作......
Expression of TRPV1 in peripheral blood in adult chronic visceral hypersensitivety rats induced by n
Objective TRPV1 is a nonspecific cation channel of the transient receptor potential channel family and may be upregulate......
TRPV1 receptor associated with detrusor overactivity induced by partial bladder outlet obstrucion in
Background: To investigate the role of TRPV1 in the pathological process of DO induced by partial bladder outlet obstruc......
The DREAM protein attenuates CFA-induced inflammatory heat hyperalgesia via negatively regulating TR
TRPV1(transient receptor potential cation channel,subfamily V,member 1),a key molecule involved in peripheral sensitizat......
Histamine H4 receptor has been recognized to play a role in evoking peripheral pruritus.However,the ionic and intracellu......
Uterine contraction-induced pain(UCP)represents a common and severe form of visceral pain.Nerve fibers that innervate ut......
Molecular and behavioral changes in nociception in a novel rat model of neonatal inflammation for th
Background & Aims: The approach to the management of chronic pain has been empirical, primarily due to the lack of infor......
热伤害性感受器(TRPVl)无论是在病理性痛还是在正常状态下是热痛敏发生和维持的关键物质。在脊髓阶段TRPV1是由背根节神经元合成,......
会议
成年大鼠少突胶质细胞中的Nogo-A蛋白具有抑制神经元轴突生长的作用，在发育过程中Nogo-A在神经元中有广泛的分布，而神经元中的Nogo-A......
目的：本研究的目的是考察辣椒素经大鼠空肠,回肠和结肠的透过特性,并研究辣椒素受体(TRPV1)在其中所起的作用.同时也研究了辣椒素与......
Cyclin dependent kinase 5 contributes to inflammatory pain by promoting anterograde trafficking of T
The number of functional transient receptor potential vanilloid 1 (TRPV1) channels at the surface,especially at the peri......
Introduction: We observed the temperature changes, the expression of TRPV1, the changes in intracellular calcium and the......
TRPV1 in basolateral amygdala mediates visceral hypersensitivity induced by neonatal maternal depriv
Objective: A growing body of evidence demonstrates that central amygdala(CeA)plays an important role in the modulation o......
目的：探讨NGF/PLC-γ/TRPV1信号通路在腹泻型肠易激综合征模型大鼠的表达变化及痛泻安肠方的干预效应。方法：采用冰醋酸灌肠、球囊直......
[目的]探讨神经痛维持期脊髓背角辣椒素受体(transient receptor potential vanilloid type1,TRPV1)的活化形式及低频电针的干预作......
Role of TRPV1 and Multidrug Resistance Proteins in the transport of Capsaicin across Various Intesti
Objective: The aim of the study was to observe the characteristic of permeation of capsaicin across jejunum, ileum and c......
H+-sensitive proteins mediate extracellular acidification-induced Ca2+ elevation in ventricular card
OBJECTIVE Acidosis-induced [Ca2+]i transients emerged in heart ischemia is an old story.Currently, three mechanisms are ......
